The Weiser Lab
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The Weiser Lab is dedicated to advancing research on childhood cancers to provide hope and innovative treatments for affected families. We translate cancer biology into cures, giving children better futures.
Mission Statement
Our mission is to uncover the biological drivers of the most aggressive childhood cancers and rapidly translate these discoveries into precise, less toxic therapies that improve survival and long-term quality of life.
How we do this:
- Decode lethal cancer biology: We use integrated histologic, genomic, proteomic, and transcriptomic approaches to identify the biological drivers of aggressive pediatric cancers.- Translate discovery into therapy: We leverage preclinical models and collaborative clinical partnerships to advance mechanism-based, targeted treatment strategies toward clinical trials.- Protect the whole child: We develop and test therapies that reduce treatment-related toxicities while preserving anti-tumor efficacy and long-term quality of life.
Why it matters:
- Children with high-risk cancers still face unacceptably poor outcomes, and new treatments are urgently needed for those whose disease does not respond to standard therapy.- Survival alone is not enough: many children who are cured experience lifelong side effects from chemotherapy, making safer, more precise therapies essential.- Translational research accelerates impact, ensuring that discoveries made in the laboratory reach patients faster and improve both survival and long-term quality of life.
How we do this:
- Decode lethal cancer biology: We use integrated histologic, genomic, proteomic, and transcriptomic approaches to identify the biological drivers of aggressive pediatric cancers.- Translate discovery into therapy: We leverage preclinical models and collaborative clinical partnerships to advance mechanism-based, targeted treatment strategies toward clinical trials.- Protect the whole child: We develop and test therapies that reduce treatment-related toxicities while preserving anti-tumor efficacy and long-term quality of life.
Why it matters:
- Children with high-risk cancers still face unacceptably poor outcomes, and new treatments are urgently needed for those whose disease does not respond to standard therapy.- Survival alone is not enough: many children who are cured experience lifelong side effects from chemotherapy, making safer, more precise therapies essential.- Translational research accelerates impact, ensuring that discoveries made in the laboratory reach patients faster and improve both survival and long-term quality of life.
Get in Touch
At The Weiser Lab, we focus on aggressive childhood cancers and employ cutting-edge molecular techniques to discover crucial insights into tumor behavior and treatment resistance. Our primary aim is to translate these findings into clinical applications.
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